ZBTB17

Protein sy'n cael ei godio yn y corff dynol gan y genyn ZBTB17 yw ZBTB17 a elwir hefyd yn Zinc finger and BTB domain containing 17 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.13.

ZBTB17
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2LVR, 2LVT, 2LVU, 2M0D, 2M0E, 2M0F, 2N25, 2N26, 2Q81, 3M52, 4U2M, 4U2N, 5ION
Dynodwyr
Cyfenwau	ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67, zinc finger and BTB domain containing 17
Dynodwyr allanol	OMIM: 604084 HomoloGene: 2575 GeneCards: ZBTB17
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • metal ion binding • nucleic acid binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription coactivator binding • transcription factor binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • protein-DNA complex • GO:0009327 protein-containing complex Prosesau biolegol • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • multicellular organism development • gastrulation with mouth forming second • ectoderm development • IRE1-mediated unfolded protein response • negative regulation of cell cycle • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • transcription by RNA polymerase II • negative regulation of cell population proliferation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7709	n/a
Ensembl	ENSG00000116809	n/a
UniProt	Q13105	n/a
RefSeq (mRNA)	NM_001242884 NM_001287603 NM_001287604 NM_003443 NM_001324137 NM_001324138	n/a
RefSeq (protein)	NP_001229813 NP_001274532 NP_001274533 NP_001311066 NP_001311067 NP_003434	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ZBTB17.

• MIZ-1
• ZNF60
• ZNF151
• pHZ-67

Llyfryddiaeth

• "Miz-1 activates gene expression via a novel consensus DNA binding motif. ". PLoS One. 2014. PMID 24983942.
• "The role of MIZ-1 in MYC-dependent tumorigenesis. ". Cold Spring Harb Perspect Med. 2013. PMID 24296348.
• "Structural Insights into c-Myc-interacting Zinc Finger Protein-1 (Miz-1) Delineate Domains Required for DNA Scanning and Sequence-specific Binding. ". J Biol Chem. 2017. PMID 28035002.
• "Miz-1 promotes the proliferation of esophageal cancer cells via suppression of p21 and release of p21-arrested cyclin D1. ". Oncol Rep. 2016. PMID 27109891.
• "Solution structure of the 13th C2H2 Zinc Finger of Miz-1.". Biochem Biophys Res Commun. 2016. PMID 26972249.